Angélica Escobar Maldonado
CURRICULUM VITAE RESUMIDO
Cargo actual: Profesora Auxiliar, Instituto de Fisiología, Facultad de Ciencias, Universidad de Valparaíso.
Educación Superior
2016 Doctora en Ciencias Biológicas, mención Biología Celular y Molecular. Pontificia Universidad Católica de Chile.
2012 Magister en Ciencias Biológicas, mención Biología Celular y Molecular. Pontificia Universidad Católica de Chile.
2010 Químico Farmacéutico. Pontificia Universidad Católica de Chile
PUBLICACIONES
2021 Sergio Hidalgo , Nicolás Fuenzalida-Uribe , Daniela Molina-Mateo , Angélica P Escobar , Carlos Oliva , Rodrigo A España , Maria Estela Andrés , Jorge M Campusano. Study of the release of endogenous amines in Drosophila brain in vivo in response to stimuli linked to aversive olfactory conditioning . J Neurochem. 156(3):337-351. 2021.
2021 Angélica P. Escobar, Jonathan Eloy Martinez, Francisco Silva-Olivares, Ramón Sotomayor-Zárate and Pablo R. Moya. Altered grooming syntax and amphetamine-induced dopamine release in EAAT3 overexpressing mice. Front. Cell. Neurosci. Cellular Neurophysiology. 2021
2021 Natalia Sánchez, Montserrat Olivares-Costa, Marcela P Gonzalez, Roberto Munita, Angelica P Escobar, Rodrigo Meza, Mauricio Herrera-Rojas, Jessica Albornoz, Gianluca Merello, María E Andrés. Knockout or knock-in? A truncated D2 receptor protein is expressed in the brain of the functional D2 receptor knockout mouse. Article, NeuroSci. 2(2), 193-206. 2021.
2020 Escobar ADP, Casanova JP, Andrés ME, Fuentealba JA. Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors. Front Pharmacol. 18;11:57. 2020.
2019 Escobar AP, Wendland JR, Chávez AE, Moya PR. The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder. Front Pharmacol. 2019.
2019 Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, Chávez AE, Moya PR. Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology. 2019 May; 44(6). doi: 10.1038/s41386- 019-0331-x.
2017 Escobar AP. The Role of Kappa Opioid Receptors in Glutamate Input Selection in the Ventral Striatum. J Neurosci. 2017 Nov 15; 37 (46):11072-11073. doi: 10.1523
2017 Escobar AP, González MP, Meza RC, Noches V, Henny P, Gysling K, España RA, Fuentealba JA, Andrés ME. Mechanisms of kappa opioid receptor potentiation of dopamine D2 receptor function in quinpirole-induced locomotor sensitization in rats. Int J Neuropsychopharmacol. 2017 Aug 1; 20 (8):660-669. doi: 10.1093
2015 Escobar AP, Cornejo FA, Olivares-Costa M, González M, Fuentealba JA, Gysling KG, España RA, Andrés ME. Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function. J Neurochem. 2015 Sep; 134 (6):1081-90. doi: 10.1111
2012 Escobar Adel P, Cornejo FA, Andrés ME, Fuentealba JA. Repeated treatment with the kappa opioid receptor agonist U69593 reverses enhanced K+-induced dopamine release in the nucleus accumbens, but not the expression of locomotor sensitization in amphetamine-sensitized rats. NeurochemInt. 2012 Mar; 60 (4):344-9. doi: 10.1016
PROYECTOS DE INVESTIGACIÓN
2019-2021 “Impact of the neuronal glutamate transporter EAAT3 on dopamine system” Proyecto FONDECYT postdococtorado #3190843
MEMBRESIAS
2018 Sociedad de Farmacología de Chile (SOFARCHI).
2021 Centro de Neurobiología y Fisiopatología Integrativa (CENFI)